Publications from the Bio-Chemistry lab in the area of Apoptosis

  1. Chromium(III) induced abnormalities in lymphocyte proliferation : Evidence for apoptosis. Rama Rajaram, B.U.Nair and T.Ramasami., Biochem. Biophys. Res.Commun. (1995) 210, 434-439

  2. Hydroxopentamminechromium(III) promoted phosphorylation of bovine serum albumin: Its potential implications in understanding the biotoxicity of chromium. K. Balamurugan, C. Vasant, Rama Rajaram and T. Ramasami.Biochim.Biophys.Acta, (1999) 1427(3), 356-365

  3. Inhibition of collagenase by Cr(III): its relevance to stabilization of collagen. R. Gayatri, Rama  Rajaram and T. Ramasami. Biochim. Biophys. Acta, (2000) 1524,  228-237

  4. Stabilisation of Cr(V) in bovine serum albumin matrix. Rama  Rajaram, K.M. Ananth and T.  Ramasami. Biochem. Biophys. Res. Commun. (2000) 273, 1138-1143.

  5. Apoptosis of lymphocytes in the presence of Cr(V) complexes: Role in Cr(VI)  induced toxicity. Vasant, C., Balamurugan, K., Rama  Rajaram, and Ramasami, T. Biochem. Biophys. Res. Commun. (2001) 285, 1354-1360

  6. Chromium(III)-induced apoptosis of lymphocytes: Death decision by ROS and Src-family tyrosine kinases. K. Balamurgan, Rama Rajaram, T. Ramasami and Sujatha Narayanan. Free Radic. Biol. Med. (2002) 33, 1622-1640.

  7. Apoptosis of lymphocytes induced by chromiuym(VI/V) is through ROS mediated activation of Src-family tyrosine kinases and caspase-3. C. Vasant, Rama Rajaram and , T. Ramasami. Free Radic. Biol. Med. (2003) 35(9) 1082-1100.

  8. Caspase-3: its potential involvement in chromium(III)-induced apoptosis of lymphocytes. K. Balamurgan, Rama Rajaram and T. Ramasami. Mol.  Cell. Biochem. (2004) 259 43-51.

  9. Approaches to a molecular insight into Cr(III) induced apoptosis of human lymphocytes. T. Ramasami, Rama Rajaram, K. Balamurugan, C.Vasant, and K.M. Ananth. Proc. Indian. Natl. Sci. Acad 70, A (2004) 343-353

  10. Non-enzymatic phosphorylation of bovine serum albumin by Cr(VI) complexes:   Role in Cr (VI)   induced phosphorylation and toxicity. C. Vasant, S .Sankaramanivel, M. Jana, Rama Rajaram, T. Ramasami. Mol.Cell. Biochem. 275 (2005) 153-164.

  11. A family knockout of all four Drosophila Metallothioneins reveals a central role in copper homeostasis and detoxification. D.Egli, H.Yepiskoposyan, A.Selvaraj, K.Balamurugan, Rama Rajaram, A.Simons    Multhaup, S.Mettler, A.Vardanyan, O.Georgiev, W.Schaffner. Mol.Cell.Biol. (2006) 26(6) 2286-2296

  12. Copper homeostasis in Drosophila by complex interplay of import, storage and   behavioral avoidance. K.Balamurugan, D.Egli, H. Hua, Rama Rajaram, G. Seisenbacher, O.Georgiev,  W. Schaffner. The EMBO Journal 26 (2007) 1035- 1044