CSIR-Central Leather Research Institute
Dr.M.S.Kiran
Scientist
Academic Qualifications
    MPhil, Ph.D
Contact Details
Dr.M.S.Kiran
Scientist

Biological Material Laboratory
CSIR-Central Leather Research Institute
Adyar, Chennai – 600 020
e-mail: kiranmsk112@gmail.com, kiran@clri.res.in,
Phone:91-44-22542490


Qualification
 

MSc (Biochemistry) University of Kerala (2002)

MPhil (Biochemistry) University of Kerala (2004)

PhD (Biochemistry) University of Kerala (2008)

Area of Interest:
 
  • Cell-Extracellular matrix interactions
  • Cell-cell interactions,
  • Angiogenesis,
  • Nanoparticles
Title of the Ph.D thesis
 
  • ‘Matrix Metalloproteinases of endothelial cells and their role in angiogenesis’ PhD Mentor ‘Professor P.R.Sudhakran, Dean, Faculty of Sciences, Head, School of Biological Sciences , Central University of Kerala.

            Professional Affiliations

 
  • Society of Biological Chemistry SBC (I)
  • Biophysical Society of Japan
  • Life Member, Kerala Academy of Sciences
  • Life Member, Indian Society for Arteriosclerosis Research

            Invited talks

 
  • Invited Speaker- IXth International Symposium on "Biochemical Roles ofEukaryotic Cell  Surface Macromolecules" Non-invasive characterization of Cell wall dynamics Saccromycetes cerevisiae   using Surface Enhanced Raman Scattering Spectroscopy. 27th-31st January 2011, Estuary Island Resort, Poovar, India.

Publications in Peer Reviewed Journals

1

Kiran MS, Viji RI, Kumar SV, Prabhakaran AA, Sudhakaran PR. Changes in expression of VE-cadherin and MMPs in endothelial cells: Implications for angiogenesis. Vasc Cell. 2011 Feb 14;3(1):6.

2

Kumar VB, Viji RI, Kiran MS, Sudhakaran PR. Angiogenic effect of laminin involves modulation of cyclooxygenase-2 and prostaglandin levels. Exp Biol Med (Maywood). 2011 Jan;236(1):44-51.

3

Kiran MS, Itoh T, Yoshida K, Kawashima N, Biju V, Ishikawa M. Selective detection of HbA1c using surface enhanced resonance Raman spectroscopy. Anal Chem. 2010 Feb 15;82(4):1342-8.

4

Sujith A, Itoh T, Abe H, Yoshida K, Kiran MS, Biju V, Ishikawa M. Imaging the cell wall of living single yeast cells using surface-enhanced Raman spectroscopy. Anal Bioanal Chem. 2009 Aug;394(7):1803-9.

5

Kumar VB, Viji RI, Kiran MS, Sudhakaran PR. Negative modulation of eNOS by laminin involving post-translational phosphorylation. J Cell Physiol. 2009 Apr;219(1):123-31.

6

Viji RI, Kumar VB, Kiran MS, Sudhakaran PR. Modulation of endothelial nitric oxide synthase by fibronectin. Mol Cell Biochem. 2009 Mar;323(1-2):91-100.

7

Sudhakaran PR, Viji RI, Kiran MS, Sameer Kumar VB. Endothelial cell-laminin interaction: modulation of LDH expression involves alpha6beta4 integrin-FAK-p38MAPK pathway. Glycoconj J. 2009 Aug;26(6):697-704.

8

Viji RI, Kumar VB, Kiran MS, Sudhakaran PR. Modulation of cyclooxygenase in endothelial cells by fibronectin: relevance to angiogenesis. J Cell Biochem. 2008 Sep 1;105(1):158-66.

9

Kiran MS, Viji RI, Sameer Kumar VB, Sudhakaran PR. Modulation of angiogenic factors by ursolic acid. Biochem Biophys Res Commun. 2008 Jul 4;371(3):556-60.

10

Kumar VB, Viji RI, Kiran MS, Sudhakaran PR. Modulation of expression of LDH isoenzymes in endothelial cells by laminin: implications for angiogenesis. J Cell Biochem. 2008 Apr 15;103(6):1808-25.

11 Kiran MS, Kumar VB, Viji RI, Sherin GT, Rajasekharan KN, Sudhakaran PR. Opposing effects of curcuminoids on serum stimulated and unstimulated angiogenic response. J Cell Physiol. 2008 Apr;215(1):251-64.
12

Viji RI, Kumar VB, Kiran MS, Sudhakaran PR. Angiogenic response of endothelial cells to heparin-binding domain of fibronectin. Int J Biochem Cell Biol. 2008;40(2):215-26.

13

Kumar VB, Viji RI, Kiran MS, Sudhakaran PR. Endothelial cell response to lactate: implication of PAR modification of VEGF. J Cell Physiol. 2007 May;211(2):477-85.

14

Kiran MS, Sameer Kumar VB, Viji RI, Sudhakaran PR. Temporal relationship between MMP production and angiogenic process in HUVECs. Cell Biol Int. 2006 Sep;30(9):704-13.

seprator

Presentations in the Scientific meetings

 
  • Kiran, M.S., Itoh, T.,  Abe, H., Fujita, Y., Tomimoto, K.,  Biju V., Ishikawa M., “Non-invasive characterization of Cell wall dynamics Saccromycetes cerevisiae  using Surface Enhanced Raman Scattering Spectroscopy” in IXth International Symposium on "Biochemical Roles ofEukaryotic Cell  Surface Macromolecules” Estuary Island Resort, Poovar, India, January 27-31, 2011.
  • Itoh, T., Kiran, M.S., Yoshida, K., Kawashima, N., Biju V., Ishikawa M., “Selective detection of HbA1c using Surface Enhanced Resonance Raman Scattering Spectroscopy” in the 57th (Spring Meeting), Annual Meeting of the Japan Society for Applied Physics, Tokai University, Shonan Campus, Japan. Abstract (20a-K-5), March 17-20, 2010
  • Kiran, M.S., Itoh, T., Yoshida, K., Kawashima, N., Biju V., Ishikawa M., “Surface enhanced resonance Raman scattering of HbA and HbA1c: Implications for diabetic diagnosis” in the 47th Annual meeting of Biophysical society of Japan, Tokushima Bunri University, Tokushima Japan. Abstract (P71) ppS117, October 30, 2009.
  • Kiran, M.S., Sameer Kumar, V.B., Viji, R.I., Sudhakaran, P.R., “Curcumin and angiogenesis” in the “20th Annual Conference of India society for Atherosclerosis (India), Tirupathi. Abstract p 45. December 21-23rd 2007.
  • Kiran, M.S., Sameer Kumar, V.B., Viji, R.I., Sudhakaran, P.R., “Changes in Poly ADP Ribosylation of VEGF and its implications in angiogenesis” in the “ 76th Annual Meeting of the Society of Biological Chemists, Tirupathi. Abstract (BC37) p59, November 25-27th 2007. (Best Poster Award)
  • Kiran, M.S., Itoh, T., Abe, H., Biju V., Ishikawa M., “Observation of surface proteins of living single yeast cells by surface enhanced Raman scattering during cell division cycles” in the 70th (Autum Meeting) Annual Meeting of the Japan Society for Applied Physics Toyama University, Toyama City, Japan. Abstract (8p-ZM-2) pp933, September 8-11, 2009.
  • Kiran, M.S., Sudhakaran, P.R., “Proangiogenic effect of curcumin” in the “International symposium on translational research” Thiruvananthapuram. Abstract (P111) p240, December 18th -21st 2005.
  • Kiran, M.S., Sudhakaran, P.R., “Changes in MMPs & TIMPs in HUVECs in vitro: relation to angiogenesis” in the “28th All India Cell Biology Conference & Symposium on Genome Biology”, Chandigarh.  Abstract (P27) pp67, December 1-3rd 2004.
  • Kiran, M.S., Sudhakaran, P.R., “Temporal relationship between production of matrix metalloproteinases and their tissue inhibitors by endothelial cells in angiogenesis” in the “International Conference on Biotechnology and Neuroscience”, Cochin. Abstract p67, December 29-31st 2004.

Awards and Merits

  BSc Rank holder at University Level (Fourth Rank)
  MSc Rank holder at University Level (Second Rank)
  Top merit award and cash prize, (MSc) Society of Biological Chemist and University of Kerala.
  Junior Research Fellowship (CSIR/JRF/NET): Obtained by qualifying national level test (top 20% all over India) in life sciences.
  Senior Research Fellowship: Council of Scientific and Industrial Research, Government of India (2005)
  BIOQUIZ Award, University of Kerala.
  Best paper award in Biochemistry (B.S.NARASINGA RAO AWARD): 76th annual meeting of Society of Biological Chemist (I), the National Symposium on Biochemistry (2007).
  The article entitled ‘Temporal relationship between MMP production and angiogenic process in HUVECs.” published in Cell Biol. Int. was among the top 25 hottest articles and occupying 6th position among the 25 articles.
  AIST Post Doctoral Fellowship from Ministry of Education, Culture, Sports, Science and Technology, Government of Japan (2008).