CSIR-Central Leather Research Institute
Dr.S.M Jaimohan
Scientist
Academic Qualifications
    PhD (Protein X-Ray Crystallography), University of Madras (2013)
Contact Details
Dr.S.M Jaimohan
Scientist

Advanced Materials Laboratory
CSIR-Central Leather Research Institute
Adyar, Chennai – 600 020
e-mail: jai@clri.res.in,
Phone:+91 44 24437142


Qualification
 

B. Sc., Biochemistry

Advanced Diploma in Bioinformatics

M. Sc., Bioinformatics Univ. of Madras (2004-2006)

Ph. D., Protein X-Ray Crystallography, Department of Biophysics, CSIR-Central Leather Research Institute (2006-2012)

Area of Interest:
 
  • Collagen structural biology, Abnormalities and disorders due to mutations in collagen
  • Crystallographic phasing & refinement algorithms
  • Synchrotron beamline data collection strategy
  • Small Angle X-ray Scattering (SAXS)

MEMBERSHIP AND PROFESSIONAL ACTIVITIES

  • Advisory committee member in International Year of Crystallography (IYCr) 2014 organized and conducted by Tamilnadu Science and Technology Centre, Chennai, India.

COUNTRIES VISITED

  • ELETTRA - SYNCHROTRON, TRIESTE, ITALY
  • EUROPEAN MOLECULAR BIOLOGY LABORATORY- EUROPEAN BIOINFORMATICS INSTITUTE EMBL-EBI), CAMBRIDGE, U.K.

RESEARCH COLLABORATORS

 
  1. Prof. Barbara Brodsky, Tufts University, USA
  2. Prof. Kenji Okuyama, Osaka University, Japan
  3. Prof. Luigi Vitagliano, University of Naples, Italy
  4. Dr. Alexandre Gingras, University of California at San Diego, USA

MACROMOLECULAR X-RAY DIFFRACTION FACILITY

 

SNAPSHOT OF SOME COLLAGEN PEPTIDE CRYSTALS

 
PUBLICATIONS
  1. Purification, crystallization and preliminary X-ray diffraction studies of Parakeet (Psittacula Krameri) haemoglobin. Acta Cryst. (2009), F65, 1027 – 1029
    S. M. Jaimohan, M. D. Naresh, V. Arumugam, A. B. Mandal
  2. Aggregation and self assembly of non-enzymatic glycation of collagen in the presence of amino guanidine and aspirin: An in vitro study. Int. J. Biolog.   Macromolecules. (2010), 47, 402 – 409
    R. Usha, S. M. Jaimohan, A. Rajaram, A. B. Mandal
  3. Purification, crystallization, preliminary X-ray diffraction and molecular replacement studies of Catfish (Clarias Magur) haemoglobin. Acta Cryst. (2012), F68, 1371 – 1373
    S. M. Jaimohan
    , M. D. Naresh, A. B. Mandal
  4. Purification, crystallization, preliminary X-ray diffraction and molecular replacement studies of White-Breasted Water hen (Amaurornis Phoenicurus) haemoglobin. J. Chosun Natural Sci. (2013), Vol. 6, No. 4,  193-196
    G. Jagadeesan, S. M. Jaimohan, P. Malathy, S. Aravindhan

CRYSTAL STRUCTURES DEPOSITED IN PROTEIN DATA BANK (RCSB-PDB)

  1. 2EPE – Crystal structure of Hen egg white Lysozyme grown in capillary method
    M.D. Naresh, V. Subramanian, S. M. Jaimohan, A. Rajaram, V. Arumugam, R. Usha,    A. B. Mandal
  1. 2YVB – High resolution crystal structure of Hen egg white Lysozyme
    M. D. Naresh, S. M. Jaimohan, V. V. Kumar, A. B. Mandal
  1. 2ZFB – Crystal structure of Parakeet Hemoglobin (Psittacula Krameri) at pH 7.5
    S. M. Jaimohan, M. D. Naresh, A. B. Mandal
  1. 2ZP6 – Crystal structure of Bovine Insulin (Hexameric form)
    S. M. Jaimohan, M. D. Naresh, A. B. Mandal
  1. 3A59 – Structure of Haemoglobin from flightless bird (Struthio Camelus)
    S. M. Jaimohan, M. D. Naresh, A. B. Mandal
INTERNATIONAL-NATIONAL CONFERENCES / SEMINARS ATTENDED
  1. Active participant in International Symposium on Recent Trends in Macro molecular Structure and Function (ISRTMSF) during 2008 conducted by Center for Advanced study in Crystallography and Biophysics, University of Madras, Guindy campus, Chennai, India.
  2. Attended one week workshop on Collaborative Computational Project No 4 (CCP4) program during Feb΄2008 funded by BBSRC, UK conducted by Eleanor Dodson, University of York, UK and MRN. Murthy, Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
  3. Participated in poster presentation held in International Symposium on Recent Trends in Macro molecular Structure and Function (ISRTMSF) during 2010 conducted by Center for Advanced study in Crystallography and Biophysics, University of Madras, Guindy campus, Chennai, India.
  4. Active participant in International Symposium on Recent Trends in Macro molecular Structure and Function (ISRTMSF) during 2012 conducted by Center for Advanced study in Crystallography and Biophysics, University of Madras, Guindy campus, Chennai, India.
  5. Participated in 41st National Seminar on Crystallography (NSC-2012) conducted by Indian Crystallographic association, University of Madras, Guindy campus, Chennai, India.