CSIR-Central Leather Research Institute
Dr.K. Rajaram
Technical Assistant
Academic Qualifications
    PhD
Contact Details
Dr.K. Rajaram
Technical Assistant

Biochemistry & Biotechnology
CSIR-Central Leather Research Institute
Adyar, Chennai – 600 020
e-mail: rajaramk@clri.res.in,
Phone:91 44 24437136


Academic Qualifications

  • B.Sc., Biochemistry, Bharathidasan University, Tiruchirappalli (2003-2006)
  • M.Sc., Biochemical Technology, Periyar University, Salem (2006-2008)
  • M.Phil., Biochemistry, Bharathidasan University, Tiruchirappalli (2008-2009)
  • Ph.D, Biochemical Technology, Anna University, Chennai (2010-2015)


Area of Interest

  • Bioprocess and Biochemical engineering
  • Application of nanotechnology in Leather processing
  • Metabolic disorders
  1. Technical Assistant, CSIR-Central Leather Research Institute, Adyar (12.06.2017 to Till Now)
  2. Guest Lecturer, Bharathidasan University, Tiruchirappalli (05.09.2016 to 30.04.2017)
  3. Senior Research Fellow– ICMR, Anna University – BIT Campus, Tiruchirappalli (05.03.2014 to 04.09.2016)
        Project Title :
    • Isolation and characterization of antidiabetic and antioxidant compounds from Tephrosia tinctoria Pers.
    • Bioactive compounds for antioxidant and antidiabetic activity were isolated and characterized using UV, FTIR, NMR, LCMS and GCMS techniques
    • Analyzed the synergetic effect of bioactive compounds in the treatment of diabetes and oxidative stress by in vitro and in vivo studies
  4. Junior Research Fellow, Anna University-BIT campus, Tiruchirappalli (10.07.2009 to 31.03.2012).
       Project title :
    • In vitro regeneration of selected endangered medicinal plants, activity guided extraction, comparative assessment of antioxidant and antidiabetic activity.
    • Restored the endangered/rare antidiabetic medicinal plants (Tephrosia tinctoria, Caralluma fimbriata, Costus igneus and Andrographis lineata) using Plant tissue culture techniques
    • Scientifically validated and compared the antidiabetic and antioxidant activity of the above mentioned medicinal plants using cell culture and animal models

Journal Publications

  1. Sudarshana Deepa V.K., Rajaram K, Suresh Kumar P. (2016) “Ethanobotany based nanostructures used in dentistry” Letters in Applied NanoBioScience, Vol.5(3), pp. 406-421.
  2. Sudarshana Deepa V., Rajaram K., Suresh Kumar P. (2015) “Dimethyl 3, 3’, 4, 4’- tetrahydroxy-δ-truxinate isolated from the leaves of Andrographis lineata.Wall.ex.Nees suppress adipogenesis in 3T3-L1 preadipocytes for type 2 Diabetes” Pakistan Journal of Pharmaceutical Sciences” Vol.28, pp.443-448.
  3. Rajaram K., Aiswarya D.C., Sureshkumar P. (2015) “Green synthesis of silver nanoparticle using Tephrosia tinctoria and its antidiabetic activity”. Materials Letters, Vol.138, pp.251 – 254.
  4. Ronaldo A., Rajesh R., Rajaram K., Sudhakar Gandhi P.S., Sureshkumar P. (2014) “Antiproliferative effects of Plumbago rosea and its purified constituent Plumbagin on SKMEL 28 Melanoma cell lines”. Pharmacognosy Research, Vol.6(4), pp.312-319.
  5. >Latha S*, Rajaram K*, Sureshkumar P. (2014) “Hepatoprotective and antidiabetic effect of methanol extract of Caralluma fimbriata in streptozotocin induced diabetic albino rats” International Journal of Pharmacy and Pharmaceutical Sciences, Vol.6(1), 665-668.
  6. Rajaram K. (2013) “Antioxidant and antidiabetic activity of Tectona grandis Linn. in alloxan induced albino rats” Asian Journal of Pharmaceutical and Clinical Research, Vol.6(3), pp.174-177.
  7. Rajaram K., Moushmi M., Velayutham Dass Prakash M., Kumpati Premkumar., Ganasaraswathi M., Sureshkumar P. (2013) “Comparative bioactive studies between wild plant and callus culture of Tephrosia tinctoria Pers.” Applied Biochemistry and Biotechnology, Vol.171(8), pp.2105-2120.
  8. Sudarshana Deepa V., Rajaram K., Suresh kumar P. (2013) “In vitro and in vivo antidiabetic effect of Andrographis lineate Wall. Ex. Nees and Andrographis serphyllifolia Wt. Lc leaf extracts” African Journal of Pharmacy and Pharmacology, Vol.7(29), pp.2112-2121.
  9. Ramkumar S., Sureshkumar P., Mandal A.K.A., Rajaram K., Mohankumar P. (2012) “Identification of superior varieties of tea (Camellia sinensis (l.) o. kuntze) in the selected UPASI germplasm using biomarkers” Journal of medicinal plants research, Vol.6(5), pp.727-743.
  10. Rajaram K., Priya D., Sudarshana D.V., Suresh K.P. (2012) “In vitro regeneration of Caralluma fimbriata Wall by organogenesis” Australian Journal of Crop Science, Vol.6(1), pp.41-45.
  11. Sudarshana D.V., Rajaram K., Anis K.M., Soni D., Suresh K.P. (2011) “High frequency regeneration and shoot multiplication in Andrographis lineata Wall. ex. Nees: an endemic medicinal plant of South India” Journal of Medicinal Plants Research., Vol.5(20), pp.5044-5049.
  12. Rajaram K., Sriramji P, Sureshkumar P. (2015) “Micropropagation, antioxidant and antimicrobial effect of Plectranthus bourneae Gamble: An endangered medicinal plant” Journal of Chemical and Pharmaceutical Sciences, Vol. 8(1), pp.142-147.
  13. Priya D., Rajaram K., Sureshkumar P. (2014) “Evaluation of anticancer activity of methanolic extract of Caralluma fimbriata Wall. against lung cancer cell line”. World Journal of Pharmacy and Pharmaceutical Sciences, Vol. 3(4), 1263-1271.
  14. Murugesan P., Rajaram K., Victor A.S., Rajasekara Pandian M., Manoharan S. (2012) “Evaluation on anti-inflammatory effects of Ficus religiosa (linn.) in carrageen an induced acute inflammation in golden Syrian hamsters” Elixir Food Science, Vol.51A, pp.11124- 11128.
  15. Priya D., Rajaram K., Suresh K.P. (2012) “In vitro Antioxidant and Preliminary Phytochemical Studies of Caralluma fimbriata Wall.” International Journal of Pharmaceutical Research, Vol. 4 (2), pp.44-48.
  16. Rajaram K., Sureshkumar P. (2011) “In vitro antioxidant and antidiabetic activity of Tephrosia tinctoria Pers. An endemic medicinal plant of South India” Journal of Pharmacy Research, Vol. 3(4), pp.891-893.
  17. Priya D., Rajaram K., Suresh Kumar P. (2011) “Phytochemical studies and GC-MS analysis of Caralluma fimbriata wall.” International Journal of Pharmaceutical Research & Development, Vol. 3(10), pp.105-110.
  18. Rajaram K, Murugesan P., Devi K. (2011) ”Preventive effect of Sphaeranthus indicus Linn. on p-Dimethylaminoazobenzene Induced Hepatocarcinogenesis in Male Albino Rats” Elixir Food Science, Vol.35, pp.2876-2880.


Book Chapters

  1. Rajaram K., Suresh Kumar P. (2014) “Comparative assessment of in vitro antioxidant and antiproliferative activity in Morinda citrifolia fruit and commercial juice”Biotechnology – Emerging Trends, Regency Publications, A Division of Astral International Pvt. Ltd., 81, Darya Ganj, Near Hindi park, Delhi Medical Association Road, New Delhi – 110002, pp. 201 -210.
  2. Aiswarya D.C., Rajaram K and Sureshkumar P. (2014) “Biosynthesis of Silver nanoparticles using Tephrosia tinctoria for antibacterial activity against multidrug resistant pathogens”, Nanobio Pharmaceutical Technology – Applications and Perspectives, Elsevier – A division of Reed Elsevier India Pvt. Ltd., New Delhi – 110 001, pp. 105 – 110.
  3. Rajaram K, Sony D, Kavitha S and Sureshkumar P. (2016) “Plant tissue culture and Agrobacterium mediated transformation”, Handbook on Molecular and Analytical Techniques in Biotechnology. SELP Publication, Tiruchirappalli. ISBN: 978- 93-80509-82-2
  4. Tamil Elakkiya V and Rajaram K. (2016) “Green synthesis of nanoparticles”, Handbook on Molecular and Analytical Techniques in Biotechnology. SELP Publication, Tiruchirappalli. ISBN: 978- 93-80509-82-2


Conference Participated / Presented

  1. Rajaram K. Medicinal important bioactive compounds from Neem. National level biological congress on “Biotechnology: Past, Present and Future”, Jan 5th-6th, 2007, Muthayammal college of arts and science, Rasipuram, Tamil nadu, INDIA.
  2. State Level Seminar on Phytomedicines for Human health Care, Organized by Tamil Nadu Scientific Research Organisation held at Conference Hall, November 22-24, 2008, Pudukkottai, Tamil Nadu, INDIA.
  3. Rajaram K. Influence of growth regulators in micropropagation of Sida carpinifolia, 7th National level biological congress on “Biotechnology: Evolution and Revolutions”, Jan 4th-5th, 2008, Muthayammal college of arts and science, Rasipuram, Tamil nadu, INDIA.
  4. Rajaram K. Apoptotic effect of Cuscuta reflexa Roxb. on liver cancer cell line (Hep3B), National Seminar on scientific validation of medicinal plants, Jan 24th-25th,2009, Srimad andavan arts and science college, Tiruchirappalli, Tamil nadu, INDIA. 
  5. National Symposium on “Contemporary Technologies & Concepts Revolutionizing Drug Discovery Strategies” and “2nd Hands-On-Workshop on “Bio-Analytical Techniques in PK Studies – From Method Development to Data Interpretation”. Department of Ocular Pharmacology & Pharmacy, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, INDIA, 2010.
  6. Rajaram K., Priya D., Latha S., Sudarshana Deepa V. and Suresh Kumar P. In vitro regeneration of Caralluma fimbriata Wall by organogenesis, Zonal Conference on Plant Physiology, Nov 22nd, 2010, VIT University, Vellore, Tamil nadu, INDIA. 
  7. Sudarshana Deepa V., Rajaram K., Sureshkumar P. High frequency regeneration and shoot multiplication in Andrographis lineata Wall .ex.Nees: An endemic medicinal Plant. Zonal Conference on Plant Physiology, Nov 22nd, 2010, VIT University, Vellore, Tamil nadu, INDIA. 
  8. Suresh Kumar P., Jeyajothi C., Sudarshana Deepa V., Rajaram K. In vitro antioxidant and anticancer activity of Costus igneous. E.Br. Indian science Congress, Jan 3rd - Jan 7th, 2011, SRM University, Chennai, Tamil nadu, INDIA. 
  9. National Seminar on “Scientific Validation of Medicinal Plants”. Organized by Srimad Andavan Arts & Science College, Tiruchirappalli, Tamil Nadu, INDIA at Jan 24th -25th 2010.
  10. Sobana M., Rajaram K., Sureshkumar P. In silico and hairy root induction studies in Tephrosia tinctoria Pers. for anticancer activities. National symposium cum workshop on “Recent trends in structural bioinformatics and computer based drug designing”, Feb 19th-22nd, 2013, Alagappa University, Karaikudi, Tamil nadu, INDIA. 
  11. TEQIP II sponsored Faculty Development Programme on Emerging trends in biotechnology from 19-08-2013 to 25-08-2013, Department of Biotechnology, Bharathidasan Institute of Technology, Anna University, Tiruchirappalli, Tamil Nadu, INDIA.
  12. Keerthana M*, Rajaram K*, Dinesh K, Sureshkumar P. In silico anticancer studies of bioactive compounds in Tephrosia purpurea Pers. 6th National Symposium cum Workshop on "Recent Trends in Structural Bioinformatics and Computer Aided Drug Design", Feb 18th –21st , 2014, Alagappa University, Karaikudi, Tamil nadu, INDIA.
  • Senior Research Fellow - 2014,  Awarded by Indian Council of Medical Research, New Delhi (Ref. No.: 45/2/2013/BMS/TRM Dated: 21.02.2014)
  • Best Paper award – Keerthana M*, Rajaram K*, Dinesh K, Sureshkumar P. In silico anticancer studies of bioactive compounds in Tephrosia purpurea Pers. 6th National Symposium cum Workshop on "Recent Trends in Structural Bioinformatics and Computer Aided Drug Design", Feb 18th –21st , 2014, Alagappa University, Karaikudi, Tamil nadu, INDIA.