CSIR-Central Leather Research Institute
Dr.Debasis Samanta
Senior Scientist
Academic Qualifications
    Ph.D Chemistry, Jadavpur University
Contact Details
Dr.Debasis Samanta
Senior Scientist
AcSIR Assistant Professor
Polymer Science & Technology
CSIR-Central Leather Research Institute
Adyar, Chennai – 600 020
e-mail: debasis.samanta@gmail.com, debasis@clri.res.in,
Phone:+91 44 24422059


Qualification
  • M.Sc. Chemistry, University of Calcutta, India, 1999
  • Ph. D. Chemistry, NCL & IACS (Jadavpur University), India, 2005
  • Research Associate, NDSU, USA, 2005-2006
  • Research Associate, UMass, Amherst, USA, 2006-2009
Area of Interest:
  • Synthetic Organic and Polymer Chemistry
  • Surface functionalization
  • Microencapsulation for Drug Delivery
Work Experience (Teaching and Research)
Senior Scientist position - 2014-present

QHF, Project leader, 2011-2014

  • Synthesized responsive polymers for catalyst development and surface modification.
  • Developed new methodology for nanoscale functionalization of surfaces
  • Prepared microcapsules for drug delivery applications.
  • Teaching B. Tech, M. Tech (Anna University/CLRI), Ph. D. course (AcSIR).
Post Doctoral Research Experience
1.University of Massachusetts, Amhesrt, MA, USA

Post Doc, 2006-2009. Mentor: Professor Todd Emrick

  • Synthesized various biocompatible polymers by ATRP, ROMP polymerization.
  • Studied the behaviour of nanomaterials conjugated with biocompatible polymers.
  • 2. North Dakota State University, ND, USA

    Research Associate, 2005-2006. Mentor: Professor Gregory Cook.

  • Developed methodology for the diastereoselective synthesis of chromanes

  • Methodology was used for the multistep synthesis of biologically active compounds.
  • 3.IACS, Kolkata

    Research Associate, 2009-2011

  • Studied assembly process of polymeric and other materials on surfaces in nano-dimension.

  • Sponsored projects

    1. As Principal Investigator

    DST Fast Track project titled Synthesis of Thermoresponsive Ruthenium Benzylidene  Metathesis Catalysts and their Applications in Microcrack Healing and in Catalyst Recovery. Budget: Rs. 17.65 lacs. Duration: 2012-2015

    2. As Co-Principal Investigator

    DBT project under RGYI scheme titled Bioinspired Magnetic and Noble Metal-Based Hybrids Nanomaterials (MNHs): Synthesis, Functionalization and its Application to Biomedical and Environmental Biotechnology. Budget: Rs. ~40 lacs. Duration: 2013-2016.

    Patent Proposal

    D. Samanta, P. Nagaraju, P. Murugan, Md. S. Alam, S. K. Das, A. B. Mandal; Novel Ruthenium Benzylidene Poly[N-Isopropylacrylamide] Compounds and A Process for the Preparation Thereof, submitted to Delhi CSIR office in January, 2014, NF No. 0028NF2014

     

    Copyright for Chemical Education-based Software

    D. Samanta, S. N. Vasagam, A. B. Mandal; “SharpNet” (A Software/Networking Tool for Conveniently Sharing Real Research Problems and Solutions; filed for copyright protection on 17th December, 2013 by CSIR.

    Conferences Abroad
  • Y. Hu, D. Samanta, S. Hong, et al.: Abstracts of Papers of the American Chemical Society Volume: 241 Published: 2011.
  • D. Samanta, K. Kratz, T. Emrick; POLY 617: Abstracts of Papers of the American Chemical SocietyVolume:235 Published: 2008
  • G. R. Cook, D. Samanta, R. Kargbo; ORGN 316: Abstracts of Papers of the American Chemical Society Volume:232 Published:2006.
  • Presentation in Conferences in India (last three years)
    • International Symposium on Chemistry and Complexity, 2011 (IACS, Kolkata)
    • National Symposium on Chemistry, 2011 (Pondicherry University, Pondicherry)
    • National Symposium on Advances in Polymeric Materials, 2012 (SK University, A.P.)
    • TAPSUN conference, 2012 (NPL, New Delhi)
    • Chennai Chemistry Conference, 2013 (CLRI, Chennai)
    • 3rd FAPS Polymer Congress and MACRO 2013, 2013 (IISC, Bangalore)
    • National Symposium on Recent Advances in Chemistry, 2013 (Pondicherry University)

    Summary of Ongoing Projects

    (A) Institution project: surface functionalization

    Immobilization of organic and polymeric compounds on different surfaces is an important part of research for the development of biosensors, solar cell and molecular electronic devices (Samanta et al Chem. Soc. Rev. 2011, 2657). One of the most popular approaches to fabricate the device is, coating a suitable surface with polymeric compounds. In this technique, a less defined, less precise and more fragile layers of conjugated polymer is produced by using spin coating, vacuum deposition techniques etc. In an alternative approach, a self-assembled monolayer (SAM) formation technique can be used that affords a more precise and stable layer of desired compound on surfaces. Recently, we demonstrated that “graft through” approach can be utilized to perform “click” polymerization on functionalized SAM on silicon and ITO surfaces (Samanta et al. Chem. Commun. 2012, 12068). We are currently working on rapid immobilization of various oligothiophenes and other conjugated systems along with multiple triazole units simultaneously by the use of the above-mentioned methodology. We are also exploring the possibility to adapt this strategy to decorate surfaces by the attachment of different kind of conjugated, nonconjugated and semiconjugated polymeric systems for device fabrication.
    Very recently we also started working on the modification of leather surface using thermo responsive polymers. We recently demonstrated the NIPAM-based methacrylic acid polymers can be immobilized on the leather surface using Cr (III) (Samanta et al. RSC Adv., 2013, 16626). We are currently pursuing research to use this methodology for the design of smart leather.

    (B) DST project (GAP 1031): polymer-supported catalyst

    A compound or material is called thermo responsive when it undergoes physical change in presence of external thermal stimuli. Poly (N-isopropyl amide) falls in this category. Due to the thermo-responsive behaviour, polyNIPAM is less soluble in water at elevated temperature. This interesting property has been exploited for several applications like catalyst/enzyme recovery. In this case, a reaction can be performed in ambient temperature in presence of a soluble thermo responsive catalyst, and after completion of the reaction temperature of the medium can be elevated so that the catalyst can be precipitated out, recovered and reused. Recently we have submitted a patent proposal in the Delhi CSIR office in January, 2014 (NF No. 0028NF2014) on the synthesis of thermoresponsive catalyst. We are currently pursuing research to use thermo responsive polymer for designing recoverable catalyst. Particularly, we are preparing thermo responsive ruthenium based metathesis catalyst. We are also studying the catalytic activity and recoverability of those catalysts.

    (C) DBT project (GAP 1062): microcapsules

     Microcapsules, small capsules of few to several hundred micrometer diameter, are useful as carrier for biological and other important substances. Recently we developed a convenient strategy of making acid-responsive microcapsules by using functionalized single-walled carbon nanotubes that can load and unload the materials in presence of acid (Samanta et al. Chem. Commun. 2011, 11975). It was clearly observed from FESEM pictures that packing of the carbon nanotubes and formation of holes in the microcapsules are acid dependent. Releasing study of the material from microcapsules at variable pH by UV-Vis spectroscopy further confirmed the pH dependent behavior of the microcapsules. Currently we are pursuing research to use those microcapsules for drug delivery application. Particularly, since the above mentioned microcapsules are highly pH dependent and the morphology changes with the variation of pH, we plan to apply the methodology for pH-driven targeted drug delivery at the specific site of the body.

    Publications
    1. P. Murugan, M. Krishnamurthy, S. N. Jaisankar, D. Samanta,* A. B. Mandal,*
      Controlled Decoration of Surface with Macromolecules: Polymerization on Self-assembled Monolayer (SAM), Chem. Soc. Rev. 2015, DOI: 10.1039/C4CS00378K
    2. N. Pentela, P. Murugan, S. N. Jaisankar, D. Samanta,* A. B. Mandal,*
      Immobilization of ruthenium benzylidene on thermoresponsive polymer: Methodology and application, J. Organomet. Chem. 2015, 778, 42
    3. P. Murugan, S. J. Ananthakrishnan, N. Somanathan, D. Samanta* and A. B. Mandal,*
      Nanoscale functionalization of surfaces by graft-through Sonogashira polymerization, RSC Adv., 2015, 5, 4121.
    4. T. Parandhaman, A. Das, B Ramalingam, D. Samanta, TP Sastry, A. B. Mandal, S. K Das,
      Antimicrobial behavior of biosynthesized silica-silver nanocomposite for disinfection of water: A mechanistic perspective, J. Hazard. Mater., 2015,290, 117-126
    5. G Radha, D Samanta, S Balakumar, AB Mandal, SN Jaisankar,
      Single-Walled Carbon Nanotubes Decorated with Polypyrrole-TiO2 Nanocomposites, J. Nanosci Nanotechnol. 2015, 15, 3879
    6. D. Samanta,* P. Murugan, S. J. Ananthakrishnan, N. Somanathan, S. K. Das, S. N. Jaisankar, A. B. Mandal;* “Click” Polymerization on Self-assembled Monolayer: A Convenient Approach to Functionalize Various Surfaces with Polytriazole, Chem. Commun., 2012, 48, 12068.
    7. D. Samanta,* R. M. Sankar, S. N. Jaisankar, M. S. Alam, A. B. Mandal;* Acid-responsive Microcapsules: The Loading-unloading Processes, Chem. Commun., 2011, 47, 11975.
    8. D. Samanta,* A. Murali, J. prakash, P. Nagaraju, R. Ramesh, T. Mitra, A. Gnanamani, S. N. Jaisankar, R. Mohan, M. S. Alam, A. B. Mandal;* Chromium-assisted Immobilization of N-isopropylacrylamide-based methacrylic acid Copolymers to Collagen and Leather Surfaces: the Thermo-responsive Behaviour, RSC Adv., 2013, 3, 16626.
    9. N. Duraipandy, R. Lakra, S. K. Vinjimur, D. Samanta, K. P. Sai, M. S. Kiran, Caging of plumbagin on silver nanoparticles imparts selectivity and sensitivity to plumbagin for targeted cancer cell apoptosis, Metallomics, 2014, In press
    10. D. Paradesi,D. Samanta,A. B. Mandal, S. N. Jaisankar, A Novel Fuel Cell Membrane with High Efficiency, RSC Advances, 2014, 4, 26193.
    11. Md. S. Alam, A. M. Siddiq, S. S. Narayanan, S. K. Das, D. Samanta, A. B. Mandal, Synthesis and Association of Ag(0) Nanoparticles in Aqueous Nonionic Surfactant Triton X-100 Solution: A Facile Approach for Antibacterial Application, Mater. Focus, 2014, 3, 156
    12. R. M. Sankar, K. M. Seeni Meera, D. Samanta, A. Murali, P. Jithendra, A. B. Mandal, S. N. Jaisankar; The Reinforced Hydrogel for Drug Loading: Immobilization of Single-walled Carbon Nanotubes in Cross-linked Polymers via Multiple Interactions, RSC Adv., 2012, 12424.
    13. M. S. Alam, D. Samanta, A. B. Mandal; Micellization and clouding phenomenon of amphiphilic antidepressant drug amitriptyline hydrochloride: Effect of KCl, Coll. Surfaces B, 2012, 203..
    14. S. N. Jaisankar, S. Ramalingam, H. Subramani, R. Mohan, P. Saravanan, D. Samanta, and A. B. Mandal; Cloisite-g-methacrylic Acid copolymer Nanocomposites by Graft from Method for Leather Processing, Ind. Eng. Chem. Res., 2013, 52, 1379.
    15. R. Murali Sankar, K. Seeni Meera, D. Samanta, P. Jitendra, A. B. Mandal, S. N. Jaisankar; The pH-sensitive polyampholyte nanogels: Inclusion of carbon nanotubes for improved drug loading, Coll. Surfaces B, 2013, 112, 120
    16. S. Mcrae, X. Chen, K. Kratz, D. Samanta, E. Henchey, S. Schneider, T. emrick; Pentafluorophenyl Ester Functionalized Phosphorylcholine Polymers: Preparation of Linear, Two- arm and Grafted Polymer-Protein Conjugates, Biomacromolecules, 2012, 13, 2099.
    17. D. Samanta, A. Sarkar; Immobilization of Bio-macromolecules on Self-Assembled Monolayers: Methods & Sensor Applications” Chem. Soc. Rev., 2011, 40, 2567.
    18. D. Samanta, K. Kratz, T. Emrick; Controlled and Living Polymerizations in Water” in Green Polymerization Methods (Wiley-VCH), editor: Robert Mathers, A. R. A. Meier, 2011, 129.
    19. Y. Hu, D. Samanta, S. S. Parelkar, S. W. Hong, Q. Wang, T. P. Russel, T. Emrick; Ferritin–Polymer Conjugates: Grafting Chemistry and Integration into Nanoscale Assemblies, Adv. Func. Mat., 2010, 20, 3603
    20. X. Chen, S. McRae,D. Samanta, Todd Emrick; Polymer−Protein Conjugation in Ionic Liquids” Macromolecules, 2010,  43, 6261
    21. D. Samanta, R. B. Karbgo, G. R. Cook; Asymmetric Synthesis of Chromanes via Intramolecular Indium-Mediated Allylation of Chiral Hydrazones, J. Org. Chem., 2009, 747183
    22. B. M. Cooper, D. Chan-Seng,D. Samanta, X. Zhang, S. Parelkar, T. Emrick; Polyester-graft-phosphorylcholine prepared by ring-opening polymerization and click chemistry Chem. Commun., 2009, 815
    23. D. Samanta, S. McRae, B. M. Cooper, Y. Hu, J. Pratt, S. A. Charles, T. Emrick; End-functionalized Phosphorylcholine Methacrylates and their use in Protein Conjugation” Biomacromolecules, 2008, 9(10), 2891
    24. D. Samanta, K. Kratz, X. Zhang, T. Emrick; A Synthesis of PEG- and Phosphorylcholine-Substituted Pyridines To Afford Water-Soluble Ruthenium Benzylidene Metathesis Catalysts Macromolecules, 2008, 41, 530.
    25. D. Samanta, S. Sawoo, A. Sarkar; In Situ Generation of Gold Nanoparticles on Protein Surface: Fischer Carbene Complex as Reducing Agent Chem. Commun., 2006, 3438.
    26. D. Samanta, S. Sawoo, S. Patra, M. Salmain, M. Roy, A. Sarkar Synthesis of Hydrophilic Fischer Carbene Complexes as Organometallic Marker and PEGylating Agents for Protein J. Organomet. Chem., 2005, 690 (24-25), 5581
    27. D. Samanta, N. Faure, F. Rondelez, A. Sarkar; Towards “Designer” Surfaces: Functionalisation of Self-assembled Monolayer (SAM) on Colloidal Gold by Alkene Metathesis” Chem. Commun., 2003, 1186. (HOT ARTICLE)..
    Awards and Distinctions
    • Certificate of appreciation by CLRI in three consecutive years (for publications): 2012 & 2013 and 2014.
    • Invited speaker, Macro 2015 Conference, IACS, Kolkata.
    • Key note speaker, AICTE sponsored FDTP, Vel Tech University, Chennai, November 2013
    • Invited speaker in the National Symposium on Advances in Polymer Materials, 2012
    • Invited speaker, Summer Training Program for Post-graduate Students, NCNSNT, University of Madras, 2012
    • NET CSIR Junior Research Fellowship and Senior Research Fellowship, 1999.
    Team

     

    P. Nagaraju
    AcSIR Ph D student(Registered: 2013)
    Area of research: Thermoresponsive polymer synthesis for catalytic, nano and leather application

    P. Murugan
    Madras University PhD student(Registered: 2014)
    Area of research:Conjugated Polymer synthesis by coupling reaction, surface polymerization

    M. Krishnamurthy
    AcSIR PhD student(Registered:2014)
    Area of research: Polymerization on nanomaterials for solar cell and leather applications

    V. Gowri
    AcSIR PhD student(Registered:2015)
    Area of research: Thermoresponsive polymer synthesis for nano and leather applications